Webinar: Exploring the Manufacturing Classification System (MCS) with Particle Informatics
Learn how particle informatics and the Manufacturing Classification System (MCS) can help accelerate drug development, reduce risk, and improve manufacturing outcomes.
Thursday, 24th September 16:00 BST
The successful development of a new pharmaceutical product relies on a deep understanding of the relationship between molecular structure, particle properties, and manufacturing processes. From discovery through development and commercial production, decisions made around crystallisation and particle design can have a profound impact on product quality, stability, and performance.
In this webinar, we will explore how Particle Informatics is helping to transform the molecule-to-medicine journey by connecting crystallographic knowledge across traditionally separate scientific disciplines. Drawing on recently published research, Andy Maloney (CCDC) and Gavin Reynolds (AstraZeneca), will describe the Manufacturing Classification System (MCS), and demonstrate how the MCS has been linked to the Cambridge Structural Database (CSD), creating a crystallographic data thread that can cover chemical synthesis, analytical science, and formulation development.
This webinar will cover
The session will highlight how CSD-Particle tools can be used to investigate the structural factors that influence pharmaceutical particle behaviour and support more informed decision-making throughout development. Attendees will gain insights into the growing role of data-driven approaches in accelerating pharmaceutical innovation, reducing development risk, and enabling the efficient manufacture of advanced drug products.
Who should attend
- Scientists and researchers working in pharmaceutical development (solid-form science, crystallisation, formulation, process development, materials science, and informatics) who are interested in leveraging structural data to support particle and product understanding.
Read the papers
- The crystal chemistry and particle sciences of drug product processing: the Cambridge Structural Database meets the manufacturing classification system, Alexandru A. Moldovan; Pietro Sacchi; Robert Docherty; Andrew G. P. Maloney, Crystal Growth & Design (2026), DOI: 10.1021/acs.cgd.5c01622.
- A proposal for a drug product Manufacturing Classification System (MCS) for oral solid dosage forms, Michael Leane, Kendal Pitt, Gavin Reynolds and The Manufacturing Classification System (MCS) Working Group, Pharmaceutical Development and Technology (2014), DOI: 10.3109/10837450.2014.954728
- Ten years of the manufacturing classification system: a review of literature applications and an extension of the framework to continuous manufacture, Michael Leane, Kendal Pitt, Gavin Reynolds et al., Pharmaceutical Development and Technology (2024), DOI: 10.1080/10837450.2024.2342953