Solid Form Science
The solid form science team investigate tools and methods to optimise the solid form properties of potential new products including new pharmaceuticals, agrochemicals and fine chemicals.
The team contributes to publication outputs and has close links with both industry and academia to provide direction to the development of our CSD-Materials product suite.
Solid Form Science Initiatives
The Crystal Form Consortium (CFC) is a collaboration between industry and the CCDC to provide structural informatics tools and approaches for the rational design of the solid form.
The Crystal Structure Prediction Consortium (CSPC) brings together representatives from industry, academia, solution providers and data organisations to share progress, hear perspectives on the current state of CSP and discuss challenges and opportunities.
Find out about the consortia
CCDC Design Centres are long-term collaborative partnerships on the application of solid form informatics to a solid form pharma portfolio to manage risks along all stages.
Examples include the Pfizer Solid Form Design Centre (SFDC) and the Novartis Solid-State Collaborative Partnership (SSCP).
CSP Blind Test
The Crystal Structure Prediction (CSP) Blind Tests bring together scientists to advance CSP methods and overcome challenges.
Learn more about the CSP Blind Test
Aromatic Interactions in the Cambridge Structural Database: Comparison of interaction geometries and investigation of molecular descriptors as an indicator of strong interactions
Elna Pidcock, Ghazala Sadiq, Joanna Stevens, Rob Willacy
The Behaviour of Occupied and Void Space in Molecular Crystal Structures at High Pressure
Cameron J. G. Wilson, Tomas Cervenka, Peter A. Wood, Simon Parsons
The Intermolecular Interactions of Organic Fluorine Seen in Perspective
Jason C. Cole, Robin Taylor
Conformational Change in Molecular Crystals: Impact of solvate formation and importance of conformational free energies.
Wright, Sarah; Cole, Jason; Cruz-Cabeza, Aurora
Suppression of isotopic polymorphism
Nicholas P. Funnell, David R. Allan, Andrew G. P. Maloney, Ronald I. Smith, Cameron J. G. Wilson, Simon Parsons
One class classification as a practical approach for accelerating π–π co-crystal discovery
Aikaterini Vriza, Angelos B. Canaj, Rebecca Vismara, Laurence J. Kershaw Cook, Troy D. Manning, Michael W. Gaultois, Peter A. Wood, Vitaliy Kurlin, Neil Berry, Matthew S. Dyer, Matthew J. Rosseinsky