WHITE PAPER DOWNLOAD
Solid Form Informatics For Pharmaceuticals and Fine Chemicals
In this white paper we introduce a knowledge-based approach for improving effectiveness, quality and risk assessment in the development of solid formulations of drugs, agrochemicals and molecular materials.
Learn about:
- The cost of failure: we discuss the potential harm that can occur as a result of unaddressed gaps in the understanding of polymorphism in solid form behaviours, especially in late stage development and post product launch, and we review the well-renowned case studies including ritonavir and rotigotine.
- Managing risk: we look at ways to manage these risks and improve reliability of solid state development.
- The Crystal Form Consortium (CFC): we discuss how this forum aims to address the lack of rational design tools for solid form development.
- The ‘Health Check’ methodology: we explain how a pro-active evaluation of crystal structures of active ingredients is now routine in a number of organisations.
- Benefits of adopting Solid Form Informatics: we look at how it’s possible to prevent potential disasters such as that of ritonavir and rotigotine using this approach.