Check out this blog to learn “Three things solid form informatics can tell you about your drug candidate”.
Solid Form Informatics For Pharmaceuticals and Fine Chemicals
In this white paper we introduce a knowledge-based approach for improving effectiveness, quality and risk assessment in the development of solid formulations of drugs, agrochemicals and molecular materials.
Learn about:
- The cost of failure: We discuss the potential harm that can occur as a result of unaddressed gaps in the understanding of polymorphism in solid form behaviours, especially in late stage development and post product launch, and we review the well-renowned case studies including ritonavir and rotigotine.
- Managing risk: We look at ways to manage these risks and improve reliability of solid state development.
- The Crystal Form Consortium (CFC): We discuss how this forum aims to address the lack of rational design tools for solid form development.
- The ‘healthcheck’ methodology: We explain how a pro-active evaluation of crystal structures of active ingredients is now routine in a number of organisations.
- Benefits of adopting Solid Form Informatics: We look at how it’s possible to prevent potential disasters such as that of ritonavir and rotigotine using this approach.