FAQs
For questions not addressed by a support solution here, please Contact Us. Please do include a description of the problem as well as your operating system and version.
What can we help you with?
-
Other than the library size, are there any other major factors that influence the docking time?
… chains or explicit water molecules will take longer) the number of GA runs per ligand whether or not "allow early termination" is switched on the chosen GA …
-
How do the default settings for GOLD differ in the MOE interface compared to standalone GOLD?
… from the default settings used in GOLD. These are (MOE v.s. standalone GOLD): Number of GA runs: 30 v.s. 10 Diverse Solutions: on v.s. off Flexible ligand ring …
-
Why is there a discrepancy between the final fitness score and the calculated fitness score (from individual terms) of a docking performed using the GOLD API?
… , the fitness is not always recalculated, but sometimes simply copied if no changes have been made to an individual during a previous iteration of the GA …
-
Why do I get different fitness scores for consecutive dockings with the same input files?
… GOLD determines solutions.GOLD uses a Genetic Algorithm (GA) for protein ligand docking which works as follows: A population of potential solutions (i.e. possible …
Top Support Solutions
- CSD Portfolio software suites requirements and supported platforms
- What is the difference between the GoldScore, ChemScore, ASP and ChemPLP scoring functions provided with GOLD?
- How do I sign into WebCSD and what are the benefits of signing in?
- How does the GOLD licensing system work?
- How should I reference GOLD?
Newest Support Solutions
- The 2024.3 CSD Portfolio software does not start on linux under Wayland and gives a Qt mismatch error
- ConQuest will not start when used with the latest version of VMWare
- Unable to run the CCDC maintenance tool on macOS 15
- CSD Python API not working on RHEL 9
- ConQuest fails with "ValueError: No JSON object could be decoded" on RHEL 8