Alessia Bacchi received her PhD in Chemical Sciences at the University of Parma in 1991 with a thesis on the correlation between molecular conformation and crystal packing for cage coordination compounds. She then moved to EMBL in Hamburg for a post-doctoral research on validation of high resolution protein structures in the laboratory of Prof. Keith Wilson. She returned in 1996 as a post-doctoral research fellow at the University of Parma, where she became Associate Professor in 2001. At the University of Parma she teaches General Chemistry and Structural Chemistry. In 2000 she was awarded the Italian Crystallographic Association prize for her studies on the correlations between molecular structure and crystal packing as a model for the analysis of complex systems. She has served as chair or member in scientific boards and committees of the International Union of Crystallography, the European Crystallographic Association, the Italian Crystallographic Association, the Italian Chemical Society. She was the Chair of the Commission of Structural Chemistry of the International Union of Crystallography in the years 2001-2011; she was member of the Executive Committee of the European Crystallographic Association in the years 2009-2012, then becoming Vice-President; since 2016 she is the President of the European Crystallographic Association.
Alessia Bacchi’s research activity is documented by more than 150 publications on international scientific journals, 5 book chapters, and presentation of more than 150 communications to national and international scientific meetings, including more than 70 oral communications presented personally, among which more than 40 have been on invitation. In addition to scientific publications, she co-authored a textbook of General Chemistry and curated the book of the exhibition CRISTALLI! Her present main research interests are focused on crystal engineering of polymorphs, solvates, co-crystals, and of responsive hybrid organic/inorganic materials. Within this broad theme she developed crystalline molecular materials capable to reversibly capture and release volatile solvents in a solid/gas exchange, and proposed structural models to map the process of molecular recognition between the crystalline receptor and the volatile substrate. Recently she has focused on the design and control of crystal forms of molecular compounds, and on the stabilization inside crystalline structures (MOF and cocrystals) of liquid and volatile compounds related to human health, environment and nutrition. She is also involved in transfer of technology regarding the characterization of crystal forms of drugs for applied researches on formulation of drugs and for support in legal issues concerning patents and intellectual property. Along with scientific production, Alessia Bacchi is actively committed to activities of outreach and divulgation towards schools and general public, having been involved in the organization of several events and public lectures. She was the national coordinator for the activities of the International Year of Crystallography in 2014, and in the same year she curated the exhibition CRISTALLI! in Parma, scoring 12500 visitors in 7 weeks. In 2015 she established the Museum of Crystallography at the University of Parma, of which she is currently the Director.
CAPUCCI Davide, BALESTRI Davide, MAZZEO Paolo Pio, PELAGATTI Paolo, RUBINI Katia, BACCHI Alessia (2017). Liquid Nicotine Tamed in Solid Forms by Cocrystallization. CRYSTAL GROWTH & DESIGN, vol. 17, p. 4958-4964
BACCHI,Alessia, PELAGATTI Paolo (2016). Fabricating organometallic wheel-and-axle compounds for the creation of dynamically porous crystalline materials. CRYSTENGCOMM, vol. 18, p. 6114-6123
BACCHI Alessia, PELAGATTI Paolo (2016). Organometallic chemistry meets crystal engineering to give responsive crystalline materials. CHEMICAL COMMUNICATIONS, vol. 52, p. 1327-1337
BACCHI Alessia, CAPUCCI Davide, GIANNETTO Marco, MATTAROZZI Monica, PELAGATTI Paolo, RODRIGUEZ-HORNEDO Nair, RUBINI Katia, SALA Andrea (2016). Turning Liquid Propofol into Solid (without Freezing It): Thermodynamic Characterization of Pharmaceutical Cocrystals Built with a Liquid Drug. CRYSTAL GROWTH & DESIGN, vol. 16, p. 6547-6555
MICHELI Fabrizio, BACCHI Alessia, BRAGGIO Simone, CASTELLETTI Laura, CAVALLINI Palmina, CAVANNI Paolo, CREMONESI Susanna, DAL CIN Michele, FERIANI Aldo, GEHANNE Sylvie, KAJBAF Mahmud, MARCHIO' Luciano, NOLA Selena, OLIOSI Beatrice, PELLACANI Annalisa, PERDONÀ Elisabetta, SAVA Anna, SEMERARO Teresa, TARSI Luca, TOMELLERI Silvia, WONG Andrea, VISENTINI Filippo, ZONZINI Laura, HEIDBREDER Christian (2016). 1,2,4-Triazolyl 5-Azaspiro[2.4]heptanes: Lead Identification and Early Lead Optimization of a New Series of Potent and Selective Dopamine D3 Receptor Antagonists. JOURNAL OF MEDICINAL CHEMISTRY, vol. 59, p. 8549-8576
BACCHI Alessia, BOURNE Susan, CANTONI Giulia, CAVALLONE Silvia A. M., MAZZA Simona, MEHLANA Gift, PELAGATTI Paolo, RIGHI Lara (2015). Reversible Guest Removal and Selective Guest Exchange with a Covalent Dinuclear Wheel-and-Axle Metallorganic Host Constituted by Half-Sandwich Ru(II) Wheels Connected by a Linear Diphosphine Axle. CRYSTAL GROWTH & DESIGN, p. 1876-1888