• A valentine-related review of the Cambridge Structural Database

    This week’s blog has a valentine’s theme. Some of you may ask what the Cambridge Structural Database (CSD) has to do with romance…well the link is tenuous, but love and romance are all about chemistry!! Of course, this creates the perfect excuse to explore Valentines related crystal structures in the CSD.

    Some say love is blind, but in fact, the biochemistry of attraction is quite complex and the subject of a lot of research. Two important compounds that play a role are Serotonin and Oxytocin. The former improves our mood and makes us feel good, certainly a good foundation for relationships. While the freebase is not in the CSD, there is a salt listed, Refcode HTRCRS, that is interesting. Bonding and trust building between mammals involves Oxytocin (DUPFAV), which has the nickname ‘the love hormone’. It also has other physiological functions, the most well-known in that it initiates labor during pregnancy.
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  • Montreal Bound

    ​This is my first blog entry for the CCDC. I am proud to say that it is a first from the US office – Paul’s previous blog entry doesn’t count as he transferred over from our Cambridge office in the UK. In the six months I have been with the CCDC I have learned a lot, and found it an impressive place to work. More importantly, I’ve now had the chance to interact with quite a few of our US customers. I am continually amazed at how well-respected the organization is by our customers, depositors and contributors. I hope that we can make sure this continues to be the case.

    The ramping up of our North American operation coincides with the UNESCO International Year of Crystallography and the 23rd IUCr Congress being in Montreal this year (where it was last held in 1957!). There will be several CCDC staff members there, from both the US and UK, so if you’re attending please come and see the CCDC exhibition stand at booth 213/215!

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