GOLD: Docking Examples

NADPH docked into DHFR. GOLD solution is shown in blue.

A peptide-like inhibitor docked into thrombin. GOLD solution is shown in red.

A thermolysin inhibitor. The zinc ion is space-filled in white and the GOLD solution is shown in red.

This picture shows the consistency of GOLD results for simple ligands. The picture shows the results of ten consecutive dockings of GMP into RNaseT1.

Here, a peptide-like inhibitor is covalently bound to a Cys S in actinidin. The GOLD result is shown in red.

This picture shows the result of the cavity detection algorithm. The surface in red is the solvent accessible surface at a radius of 16 Angstrom. The area in grey is the surface detected by the cavity detection routine.